Clozapine involved with risk of serious constipation

There has been a report of a fatality caused by clozapine-induced constipation and a warning has been issued: http://www.wales.nhs.uk/sites3/documents...

Constipation is a common side-effect of clozapine and in this case the patient was also taking pirenzapine which can also cause constipation.

All patients prescribed clozapine should be monitored for side-effects, including constipation. Ashtons has produced a Clozapine Information Guide which is available upon request, simply click to contact us